Behavioral evaluation of transgenic mice with CNS expression of IFN-α by elevated plus-maze and Porsolt swim test
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چکیده
منابع مشابه
Elevated Plus Maze for Mice
Although the mouse genome is now completely sequenced, the functions of most of the genes expressed in the brain are not known. The influence of a given gene on a specific behavior can be determined by behavioral analysis of mutant mice. If a target gene is expressed in the brain, behavioral phenotype of the mutant mice could elucidate the genetic mechanism of normal behaviors. The elevated plu...
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Systematic observations of the defensive behavior of wild rodents have greatly informed the experimental study of anxiety and its neural substrates in laboratory animals. However, as the former work has been almost exclusively carried out in rats, few data are available concerning the reactivity of wild mice to standardized tests of anxiety-related behavior. In the present experiments, we emplo...
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ژورنال
عنوان ژورنال: Neuroscience Letters
سال: 2010
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2010.05.082